The Field Spaniel Society
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September 2016 - Communication from AHT regarding where we are now.
The team at AHT are collating the returned information from 66/75 breeds and 80 disorders so far listed. This is a time consuming process involving a review of current literature for all 80 conditions listed and communication with other scientists working on some of these conditions
This will allow them to decide on which healthy control dog and which with a disorder they choose to sequence. Once they have determined which dogs to sequence they will advise us regarding the DNA samples required.
The process will take a number of months for all 75 breeds, so they are proceeding in smaller batches to keep up the momentum.
The Field Spaniel Committee are very pleased to announce that we have been accepted onto the "Give A Dog A Genome" project. The project is a collaboration between the Kennel Club Charitable Trust and the Animal Health Trust ( AHT ) and initially 50 dog breeds have been invited to take part. One dog will be selected from each breed by the AHT and DNA from these dogs will be used to sequence the entire genome of these breeds, during 2016.
I spoke to Dr Cathryn Mellersh today at the AHT and she tells me that the information gained will provide genetic markers that can be used to aid our understanding of the variation within the canine genome. In the future scientists will be able to identify disease mutations and this in turn will aid both prevention and hopefully cures for disease.
This is a very exciting time and I will bring you further information and updates as our participation in the project progresses.
Further Links for Information regarding this can be found at the AHT site .
Give a Dog A Genome
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What is Give a Dog a Genome?
Every genome we sequence is a permanent resource which will contribute towards our research for many years to come, to the benefit of all breeds – not just those we can sequence now.
By undertaking this colossal task - DNA is a string of A, C, G & Ts…if each was 1mm long the whole genome of each dog we sequence would stretch from Lands End to John O’Groats and back again! - we will enhance our understanding of which changes in DNA sequence have an effect on dog health and which changes are benign or neutral.
This information will have profound effects on our ability to identify mutations which cause inherited diseases in purebred dogs, and the rate at which we can develop new DNA tests as tools for breeders. Give a Dog a Genome will revolutionise canine genetics research and is therefore a hugely important project to the future of dog health.
We are now progressing well with the Genome Project.
The next step now is to give the details of 3 dogs/bitches to take part. So we are now asking members if they would be willing to put their dogs forward to take part in this project.
To become involved the criteria is
A) The dogs/bitches must be 8 years or older, appear in good health, with no known chronic or hereditary conditions
B) Be prepared to have a full BVA eye examination incl. Gonioscopy. The cost of this will be refunded,
C) Give details of a 5 generation pedigree.
We are of course on a deadline and so I would ask those of you who wish to be considered to pass their details on to our Health Supervisor, Mrs H Weeks email@example.com.
Once the details have been received all participants will be put together and 3 picked at random to go forward to the AHT.
The deadline for this will be the 3rd March 2017.
I would like to clarify that all information is dealt with in the strictest confidence.
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